Steep Path Toward a Synodal Church

Latinos, Education, and the Church: Toward a Culturally Democratic Future

A path toward understanding neurodegeneration.

T he specter of neurodegenerative disease, particularly Alzheimer’s disease, haunts the developed world and exacts a poorly documented toll on underdeveloped countries. With so little progress made toward finding a cure— or, better, a prevention—it is time to rethink the path to progress. This requires a change in perspective on the type of research that will make a difference. The lesson learn...

A Collective Path toward Regeneration

How do cells collectively control an organ's behavior? By plucking various numbers of hairs from the mouse skin, Chen et al. show that hairs regenerate only when a sufficiently high density of them are plucked. Remarkably, a hair follicle can only regenerate in concert with other follicles, but not autonomously.

Taking a lipidation-dependent path toward endolysosomes

We recently reported that the isoprenylation and palmitoylation motif present at the C-terminus of human RhoB protein promotes intraluminal vesicle delivery of proteins in cells from organisms as phylogenetically apart as fungi and humans. Here we build on these observations by showing that chimeras of fluorescent proteins bearing this sequence, namely, CINCCKVL, which become isoprenylated and ...

Toward Crowd-Sensitive Path Planning

If a robot can predict crowds in parts of its environment that are inaccessible to its sensors, then it can plan to avoid them. This paper proposes a fast, online algorithm that learns average crowd densities in different areas. It also describes how these densities can be incorporated into existing navigation architectures. In simulation across multiple challenging crowd scenarios, the robot r...